Cholesterol — Ingredients

Category: Ingredients

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One of the three essential lipids of the skin barrier, alongside ceramides and fatty acids

What is Cholesterol?

One of the three essential lipids of the skin barrier, alongside ceramides and fatty acids

Acts as intercellular cement in the stratum corneum. When combined with ceramides, barrier repair effects are maximized.

Key properties & actions

Cholesterol is known as one of the three major lipids of the stratum corneum, alongside ceramides and fatty acids. It is a key component of the lamellar structure that fills the spaces between corneocytes, and research suggests that barrier function is most stable when these three lipids are present in roughly a 1:1:1 ratio. When this balance is disrupted by aging or over-cleansing, transepidermal water loss may increase.

How to manage

Cholesterol is known to work synergistically when used in products that also contain ceramides and fatty acids, so choosing a formulation that combines all three is preferable to using a single ingredient in isolation. Applying a moisturizer immediately after cleansing while the skin is still slightly damp may help with absorption. If symptoms of barrier damage are severe or recurring, consulting a dermatologist is recommended.

Good to know alongside

Cholesterol is grouped with ceramides and free fatty acids (such as linoleic acid) as the 'three major skin barrier lipids,' and is discussed in connection with the concepts of lamellar structure and physiological lipids.

Everyday care tips

During winter, when skin feels tight and rough, applying a thin layer of a barrier cream containing cholesterol as the final step in your routine may help maintain moisture.

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Frequently Asked Questions (FAQ)

What is Cholesterol?
One of the three essential lipids of the skin barrier, alongside ceramides and fatty acids. Acts as intercellular cement in the stratum corneum. When combined with ceramides, barrier repair effects are maximized.

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Sources & References

Medical Disclaimer

SKINROUTE is not a medical device or healthcare provider. All content is general skincare information for reference only. If you have concerns about your skin, please consult a board-certified dermatologist.